Alpha-1 antitrypsin deficiency, AATD, is an inherited disease affecting the lung, liver, and, rarely, skin. Alpha-1 antitrypsin, AAT, is a protease inhibitor of the proteolytic enzyme elastase.

National Jewish Health researchers with the Advanced Diagnostic Laboratories have developed a molecular diagnostic test capable of accurately diagnosing a major genetic cause of chronic obstructive ...

Early emphysema due to alpha 1-antitrypsin deficiency (alpha 1-ATD) in a young patient with asthma is an unusual and frequently missed diagnosis. Theoretical and clinical evidence supports the ...

As part of the multicenter National Heart, Lung, and Blood Institute registry of patients with severe deficiency of alpha 1-antitrypsin with 1,129 enrollees, this report describes measures undertaken ...

Alpha-1 antitrypsin deficiency (AATD) is a genetic disorder characterized by the misfolding and accumulation of the mutant variant of alpha-1 antitrypsin (AAT) within hepatocytes, which limits its ...

MOLINE, Ill. — November is Alpha-1 Awareness Month, a time dedicated to increasing understanding of Alpha-1 Antitrypsin Deficiency, a rare genetic condition that can cause serious lung and liver ...

Rising prevalence of genetic respiratory disorders, expanding healthcare infrastructure, and strong R&D investments fuel sustained market growth worldwide.Austin, Texas, Jan. 13, 2026 (GLOBE NEWSWIRE) ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Studies assessing bronchoscopic lung volume reduction ...

"Our findings demonstrate that dyspnea, frequent exacerbations, and other aspects of disease severity associate with worse quality of life, particularly its physical component." -- Radmila Choate, PhD ...

Korro Bio completed dosing for its KRRO-110 study in AATD, expects interim results in 2025, and has strong financial resources. Korro Bio, Inc. has completed dosing for the first two cohorts in its ...

Alpha-1 antitrypsin deficiency (AATD) is a hereditary condition characterised by the misfolding of the alpha-1 antitrypsin (AAT) protein, resulting in its hepatic accumulation and compromised protease ...