Antigen processing and presentation is the process by which protein antigen is ingested by an antigen-presenting cell (APC), partially digested into peptide fragments and then displayed on the surface ...

Chimeric antigen receptor T-cell (CAR-T) therapies have emerged as a revolutionary approach in the field of hematological malignancies, offering unprecedented clinical efficacy when patients have ...

To activate T cells, DCs take up, process, and present antigens as part of major histocompatibility complexes (MHCs) that interact with T cell recep­tors. Therefore, Curtis and her team set out to ...

Since cancer can develop and progress in the presence of an intact immune system, TAAs are by definition weakly immunogenic. Cancer vaccines are designed to break immune tolerance. Strong antigen ...

BARDA funding could total $18.8 million if all milestones are met and options and extensions are made. The HHS through the Biomedical Advanced Research and Development Authority (BARDA) has awarded ...

Any substance that induces the immune system to produce antibodies against it is called an antigen. Any foreign invaders, such as pathogens (bacteria and viruses), chemicals, toxins, and pollens, can ...

The terms “process-specific” and “generic” are commonly used in scientific publications and regulatory guidelines in reference to host cell protein (HCP) analysis of recombinant biopharmaceuticals.

Antigen spreading was evaluated in a subset of Phase 2 patients to assess the ability of ELI-002 7P to broaden immune responses to personalized tumor neoantigens not present in the targeted ...

An allergen is any antigen that causes an allergic reaction. A non-allergen antigen could be a bacteria, virus, parasite, or fungus that causes an infection. This could also be something else that ...

WHO has prequalified two Covid-19 rapid antigen tests for the first time, confirming long-term quality and enabling UN ...