Oncotarget (a primarily oncology-focused, peer-reviewed, open access journal) aims to maximize research impact through insightful peer-review; eliminate borders between specialties by linking ...

Genetic variation is the foundation of human diversity, enabling differences in traits such as height, eye color, or blood type. Some sequence variants also cause inherited diseases, including sickle ...

Gene therapy has long promised to provide a solution for genetic blood disorders, but delivering on that promise has proven complex due to challenges including difficulties delivering the editing ...

A new AI model called popEVE can predict how likely each variant in a patient’s genome is to cause disease. The team is testing popEVE in clinical settings to see if it can speed accurate diagnoses of ...

A new AI tool developed by Harvard Medical School researchers could significantly improve how we diagnose and understand rare genetic diseases. Every human genome contains tens of thousands of small ...

Imagine that you have a history of breast cancer in your family, and you want a better idea of what your personal risk is. You consult your physician, and they recommend that you test to see if you ...

How would you summarize your study for a lay audience? Our study introduces a new tool called FUSE (Functional Substitution Estimation) that helps scientists better understand how changes in genes ...

An international research consortium co-led by scientists from Vanderbilt University Medical Center, the University of Toronto and University of Pittsburgh has mapped the functional impact of more ...

Cancer treatment is becoming more personalized. By considering a patient's unique genetic and molecular profile, along with their lifestyle and environmental factors, doctors can make more accurate ...