Background and Objective: Narcotic analgesics such as hydromorphone undergo an extensive first-pass effect resulting in a low systemic bioavailability following oral administration. Alternative dosing ...

Industry is adapting to the increasing complexity and poor solubility and bioavailability of molecules in the pipeline. Poor solubility and low bioavailability have hindered the development pipeline ...

When it comes to supplements, absorption matters just as much as the dosage. You could be taking the most potent multivitamin or mineral supplement, but if your body can’t absorb it properly, it won’t ...

Objective: Flavanones are polyphenols specific of citrus fruits, where they are present in high amounts. Although citrus fruits and juices are widely consumed in the world, little information has been ...

Gerry McNally is the vice president of research and development at NextEvo Naturals and a seasoned consumer health care R&D executive with a track record of leading the conception, development and ...

(Beyond Pesticides, July 23, 2024) In analyzing the interactions between neonicotinoid pesticides (NNPs) and microplastics (MPs), a recent study in The Science of The Total Environment finds that ...

MELBOURNE, Australia, Nov. 24, 2025 (GLOBE NEWSWIRE) -- Gelteq Limited (“Gelteq” or the “Company”), a clinical and science-based company specialising in gel-based oral delivery solutions, today ...

The bioavailability of pantoprazole when administered as a suspension in sodium bicarbonate solution and as the oral tablet was studied. In an open-label, randomized, two-period crossover study, ...

Model-based formulation and technology selection methodologies facilitate rapid product development. A large percentage of new chemical entities (NCEs) have physicochemical properties that require ...

Lubrizol offers an array of pharmaceutical excipients for oral, topical and injectable applications. The company’s portfolio ...