The shikimate pathway is fundamental for the biosynthesis of aromatic amino acids—tryptophan, tyrosine and phenylalanine—in plants, bacteria and fungi. This pathway, which is absent in mammals, has ...
A subset of natural products, such as polyketides and nonribosomal peptides, is biosynthesized while tethered to a carrier peptide via a thioester linkage. Recently, we reported that the biosyntheses ...
Biologists from the University of York (UK) have discovered enzymes that catalyze the biosynthesis of alkaloids in a number ...
Amino acid metabolism in the TIME. The TIME is shaped by metabolic competition between tumor and immune cells. Amino acids have key roles in modulating immune responses and tumor progression. (A) ...
Researchers are building out the repertoire of chemical reactions, using light. They report a method using photobiocatalysis to produce non-canonical (not naturally occurring) amino acids that are ...
As people grow older, the same brain chemistry that once supported sharp thinking and stable mood can quietly start to work against them. A new wave of research is revealing how a single amino acid, ...