Chemotherapy for pediatric acute lymphoblastic leukemia (ALL) induces rapid and durable alterations in cerebrospinal fluid (CSF) metabolism, and a lipid-rich CSF signature measured early in treatment ...

CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.

CIDP causes muscle weakness and numbness, among other symptoms. Diagnosing CIDP involves peripheral nervous system testing, cerebrospinal fluid analysis, and imaging. CIDP is an immune-mediated ...

In a recent study published in the journal Nature Medicine, a group of researchers assessed if a precise blood test matches or surpasses traditional cerebrospinal fluid (CSF) tests in detecting ...