Modifications of the chromatin are crucial for the regulation of nearly all DNA-templated biological processes. Single-cell chromatin modification profiling can be used to assess chromatin ...

Proof-of-concept trial in a single patient shows that cells can survive transplantation without immunosuppression ...

Epigenetics is the study of how our cells alter their function by modifying gene expression in our genetic code or deoxyribonucleic acid (DNA). In our cells, DNA is constantly being used to generate ...

The human body has to protect itself from pathogens and infectious agents, and there are a variety of ways for the immune system to sense foreign invaders, and react to the threats they may pose. But ...

A new tool called SigRM helps researchers study RNA modifications in individual cells, improving our understanding of how genes are regulated. Researchers have developed a new tool that will help ...

There is an explosion of single-cell genomics profiling technologies. Although major advances have been made in measuring gene expression and DNA accessibility, assays specific to epigenetic ...

Researchers have discovered a mark left behind in unfertilized egg cells that determine which DNA instructions will be inherited if the egg is fertilized. when these instructions are missing, enlarged ...

Researchers created atomic-level models of the spike protein that plays a key role in COVID-19 infection and immunity, revealing how the protein bends and moves as it seeks to engage receptors. When ...

Philadelphia, July 28, 2023—In a step forward in the development of genetic medicines, researchers at Children’s Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University ...