The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...

P-cadherin is a protein commonly found on malignant cancer cells and has been used as a target for antibody-based cancer treatments. UC Davis biomedical engineers have discovered that when an antibody ...

The anti-tumor immune response involves a series of complex steps mediated by various immune cells and signaling molecules. Cytotoxic T cells (CTLs), also | Cancer ...

Understanding how cells become fat cells is a crucial part of tackling conditions like obesity and type 2 diabetes – and a ...

In a major brain science breakthrough, New Orleans-based researchers and collaborators have discovered a nerve signaling mechanism that takes place outside the cell, flipping on a 'pain switch.' This ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

This specific 1-29 sequence is often referred to as the "functional fragment" because it contains the essential binding domain required to activate GHRH receptors in the pituitary gland.

Scientists have uncovered a new way embryonic cells divide when conventional mechanisms fail. Cell division underpins all ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...