As part of the body's first line of defense against foreign invaders, macrophages play an integral role in the innate immune ...

Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Macrophages use cell‑volume changes to sense danger, reprogram gene expression, and heighten inflammatory and antiviral responses.

Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, ...

Subscribe to our newsletter for the latest sci-tech news updates. One finding of the study, now published in the Journal of Biological Chemistry, surprised the researchers: The mice were ...

A hallmark of type 2 diabetes is the progressive loss of beta cell mass: cells in the pancreas that produce and release ...

Researchers have identified an unexpected mechanism that links age-related stress to the decline of blood-forming stem cells.

Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into ...

A recent study published in the journal Frontiers in Endocrinology investigated the role of the short-chain dehydrogenase/reductase 42E member 1 (SDR42E1) enzyme in regulating sterol metabolism and ...

The embryonic receptor "Smoothened" regulates dopamine and acetylcholine timing to control learning and habit formation in adults.

A study conducted in an Indian population has identified new molecular pathways that contribute to cardiovascular disease, ...