One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature.
A game-changining achievement in genome science has identified over 140,000 distinct DNA loops in our cells, providing chromosome fold resolution that is among the best ever created. In this ongoing ...
The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...
DNA inside human cells is not just floating around freely. It is tightly wrapped around small proteins, forming a long chain.
Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA – its genome – and segregate it equally ...
A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.
For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a ...
Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA and creates specific loops in the genetic material which determine the ...
Scientists depicted the four-dimensional genome model to reveal how DNA folding regulates genes. The discovery helps ...
COLUMBUS, Ohio – New mouse model research led by scientists at The Ohio State University Wexner Medical Center, College of Medicine and Imperial College London explored how nerve cells repair ...