Our discovery set comprised 31 pRCCs and paired normal tissue or peripheral blood (Table 1). Three tumours were separate foci from case GK116; these appeared to be grossly distinct lesions and were ...
A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer. This is an ASCO Meeting Abstract from the 2015 ASCO Annual Meeting ...
Patterns of distant metastases in HPV-positive head and neck squamous cell carcinoma. This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This abstract does not include a full text ...
Translocations, in genetics, happen when chromosomes break and the pieces attach to other chromosomes. This mixing of genetic material has important results. The resultant chromosomes are lacking in ...
Most cancer researchers are convinced that cancer results from a handful of genetic mutations that kick a cell into uncontrolled growth. UC Berkeley genetics researcher Peter Duesberg disagrees, and ...
Chromosomal rearrangements have a relevant role in organismic evolution. However, little is known about the mechanisms that lead different phylogenetic clades to have different chromosomal ...
An international study has identified more than 50 genes on the X chromosome in which mutations may cause poor sperm production. Nearly half of all men with low or zero sperm count have no medical ...
Cancer researchers have long treated genetic chaos and epigenetic rewiring as separate engines of disease, two parallel hallmarks that help tumors grow, spread, and resist treatment. Now a new wave of ...