The aim of this research therefore was to streamline the understanding of typical causal structures in both randomized and nonrandomized clinical trials in oncology, presenting concise guidelines for ...

In a randomized clinical trial, instead of allocating patients equally between the treatment arms, some trials in oncology assign a higher proportion of patients to receive the experimental treatment ...

In the 1940s, medical researchers began using randomized controlled trials to assess the efficacy of health interventions. In RCTs, researchers create randomly assigned treatment and control groups, ...

Please provide your email address to receive an email when new articles are posted on . JAMA+ Trials is intended to invigorate dialogue about trials and showcase the effort behind them, its editor in ...

Twice-yearly mass distribution of azithromycin to children is a promising intervention to reduce childhood mortality in sub-Saharan Africa. The World Health Organization recommended restricting ...

A New York Times health reporter explains what clinical trials are, why they are important and how they can help inform us. Credit...Ricardo Tomás Supported by By Nina Agrawal Nina Agrawal is a health ...

In this multicenter, open-label, randomized, controlled trial in China, we assigned participants with newly diagnosed Kawasaki disease in a 1:1 ratio to receive prednisolone plus standard treatment or ...