The complement system represents a cornerstone of innate immunity, comprising a cascade of plasma proteins that, upon activation, facilitate pathogen clearance and coordinate inflammatory signalling.

A research team at the Medical University of South Carolina reports in Cells that the complement system, part of the body's natural immune defenses, is a key driver of inflammatory responses that ...

Levels of C4d and C4d/C4 associate with clinical and histopathological treatment response in proliferative lupus nephritis. Complement activation markers, particularly C4d and the C4d/C4 ratio, are ...

The complement system is an innate immune response that leads to increased inflammation. The drug pegcetacoplan—a complement inhibitor—was approved for medical use in the United States in 2021 to ...

Serum calprotectin and complement factor 3 (C3) levels were elevated in treatment-naive patients with early psoriatic arthritis (PsA) and declined with treatment; these markers outperformed C-reactive ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

Tomatoes and bell peppers both provide many anti-inflammatory antioxidants. They're rich in lycopene, vitamin C and other ...

New research published in ImmunoHorizons shows that running a high-intensity interval training (HIIT) workout triggers a more inflammatory immune response than cycling HIIT. These findings could help ...