New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with later life and link to aging markers. Mitochondria are ...

Euan Ashley's lab explores the intricate interactions of gene variants. Tiny "typos," or genetic mutations, can sneak into segments of DNA. Many of these are harmless, but some can cause health ...

Scientists at The University of Texas at Austin have developed a revolutionary gene-editing method using bacterial retrons that can correct multiple disease-causing mutations at once. Unlike ...

Mayo Clinic researchers have developed a promising gene-editing therapy that directly corrects a genetic mutation responsible for autosomal dominant polycystic kidney disease (ADPKD), the most common ...

Scientists have pinpointed precise regions in the human genome where DNA is most likely to develop a mutation. At spots where RNA polymerase 'opens' your DNA to read and copy instructions – known as ...

As we age, our cells accumulate DNA mutations. If any of these mutations confer a growth advantage to a self-renewing or long-lived progenitor cell, its lineage can expand. The progenitor cells that ...