Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we ...

A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as a kind of "traffic controller" on DNA. Without this protein, chaos ensues, ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

A new mouse study found that unrepaired DNA-protein crosslinks activate inflammatory signaling pathways that trigger early aging disorders.

Using single-cell epigenomic profiling of immune cells from 110 individuals, researchers show that genetic variation and ...

If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by researchers at Goethe ...