For decades, biologists have known that the instructions for life are written in DNA, yet the vast majority of those letters seemed to sit in the dark, doing little that was obvious. Now a new ...

Trained on 9 trillion DNA base pairs from every domain of life, the Evo 2 model can predict disease-causing mutations, identify genomic features and generate entirely new genetic sequences.

EMBL researchers created SDR-seq, a next-generation tool that decodes both DNA and RNA from the same cell. It finally opens access to non-coding regions, where most disease-associated genetic variants ...

DNA sequencing is one of today's most critical scientific fields, powering leaps in humanity's understanding of genetic causes of cancer, neurodegenerative diseases, and diabetes. One issue facing the ...

A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act like molecular anchors. The work confirms these tags actively silence genes, ...

A new gene-editing technique enables the correction of multiple genetic mutations simultaneously, transforming the prospects for millions living with complex inherited diseases, such as cystic ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Investigators in the Nancy Guthrie case have turned to genetic genealogy as they try to make the most of potential DNA ...

All the cells in an organism have the exact same genetic sequence. What differs across cell types is their epigenetics-meticulously placed chemical tags that influence which genes are expressed in ...