Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...
Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer. Every day, billions of cells in your body ...
Morning Overview on MSN
Cancer’s most notorious protein MYC quietly repairs the DNA damage chemo inflicts — block that trick and treatment could hit tumor cells far harder
Chemotherapy drugs like doxorubicin and etoposide work by snapping a cancer cell’s DNA in two. The breaks are supposed to be lethal. But in tumors that overexpress the oncoprotein MYC, and that ...
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