The Metabolic Disease Laboratory provides services for the diagnosis of lysosomal storage diseases. The laboratory provides screening of urine for glycosaminoglycans, oligosaccharides, sialic acid, ...

During the last 50 years, an abundance of data has been gathered on the function of lipids as a source of energy, as building blocks, and as signaling molecules in living systems. Lipid-signaling ...

Histone deacetylase (HDAC) enzymes play a critical role in normal gene-regulation events and the maintenance of homeostasis. However, their dysregulation has been implicated in a variety of disease ...

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl ...

Kanazawa University, have captured real-time images showing how a key brain enzyme organizes itself to help memory formation.

Today's gold standard for COVID diagnostics is qRT-PCR, but turnaround is typically more than a day. Newer assays using CRISPR enzymes require initial amplification of RNA, requiring special equipment ...

Researchers at the Centre for Genomic Regulation have developed a new technique for identifying allosteric sites in proteins (Nature 2022, DOI: 10.1038/s41586-022-04586-4). While many drugs target the ...

Molecular diagnostic tests are currently used for infectious disease testing due to the superior sensitivity and specificity that can be obtained. Due to the success that has been obtained with this ...

A photo illustration shows Weixue Wang surrounded by a protein structure and an assay. Credit: Will Ludwig/C&EN/Tim Peacock/Scorpion Therapeutics There's a thread running through Weixue Wang's ...