In practical applications, nothing determines the success of a biocatalysis project more than the precise match between the enzyme and the substrate. Many industrial projects encounter issues such as ...

Complementary biochemical and structural findings reveal molecular principles underlying substrate selectivity by a model hyaluronan synthase.

Researchers at the University of Basel have repurposed a natural enzyme so that it catalyzes a highly challenging chemical reaction. Their approach opens new possibilities for synthesizing complex ...

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists have now derived universal rules to enable the de novo design of optimal enzymes. As an example, they ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...