Growing from a single cell into a complex organism with specialized tissues and organs requires a complex and coordinated process. But the mechanical signals that guide tissue and organ ...

A new study, led by Prof. Liu from the department of pharmacy, University of Electronic Science and Technology of China, discovered that the extracellular cell matrix (ECM) could induce the drug ...

Ultrasound-mediated nanobubbles improve cancer therapy by softening tumors, enhancing lipid nanoparticle distribution, and ...

Amyotrophic lateral sclerosis and frontotemporal dementia are heterogeneous diseases that are difficult to fully model in mice. One of the more common forms is caused by hexanucleotide repeat ...

Cartilage injuries are a common clinical issue, often caused by trauma, severe infections, or degenerative joint diseases. The lack of direct blood supply to cartilage and limited access to nutrients ...

In cell and animal models of amyotrophic lateral sclerosis (ALS), the expression of toxic dipeptides in neurons led to changes in the extracellular matrix (ECM) as a protective response. The authors ...

Researchers suggest targeting ECM-mediated regulation of autophagy levels could be used to sensitize pancreatic cancer to FDA-approved therapies.

This neon tapestry of red and blue is a unique look at the space between cells in the body known as the extracellular matrix. This image was created using a new labeling technique that allows ...