Paired box 6 (PAX6) is a member of the highly conserved paired box (PAX) transcription factors. Transcription factors regulate the activity of large numbers of genes involved in development. The PAX6 ...

Mentor: Michael L Robinson, Ph.D. This project explores the role of FOXE3 in eye development, focusing on its potential influence on cell fate decisions. Key questions include: What is the role of ...

Researchers have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization, each cell has the ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

In the earliest hours after fertilization, an embryo takes its first steps toward becoming a living organism by shedding maternal control and activating its own genetic program. This critical process, ...