Scientists have found an essential factor from the extracellular matrix that regulates functionality of the breast tissue for instance during pregnancy. Scientists at the University of Helsinki have ...

Matrix metalloproteinases (MMPs) are a family of extracellular, zinc-dependent endopeptidases that have emerged as pivotal regulators of neural plasticity and synaptic function. In the brain, MMPs ...

Between and around the billions of neurons in the human brain is an equally vital scaffold, the extracellular matrix (ECM). An interlinked net of proteins and sugars that surrounds brain cells, the ...

In a recent study, led by corresponding author, Anna-Maria Liphardt, PhD, of the Rheumatology and Immunology Department at Friedrich-Alexander-Universität Erlangen-Nürnberg and the ...

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to ...

For in vitro cellular assays, the extracellular matrix—the material between cells—often is overlooked, but changes within this microenvironment affect cells’ proliferation and differentiation and, ...

Cartilage injuries are a common clinical issue, often caused by trauma, severe infections, or degenerative joint diseases. The lack of direct blood supply to cartilage and limited access to nutrients ...

Collagens and elastin in the extracellular matrix, which forms a scaffold to support organs, cause the immune system's natural killer cells to switch off their 'killer' function. The hypertension drug ...

This review innovatively proposes the use of electrospinning to fabricate electroactive fibrous scaffolds, which mimic the structure of the extracellular matrix while providing electrical activity, ...