A newly discovered promoter element "start" points to a shared regulatory syntax for controlling transcription initiation in ...
Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to ...
A shared molecular signature of Alzheimer’s appears across populations once studied in isolation. Alzheimer's disease (AD) ...
It often involves the introduction of genetic material into a person’s cells to replace a defective or missing gene. Although early attempts at gene therapy have been effective in achieving the ...
Mice and newts were applied to the one-step Cre-loxP organism creation technology by TAx9. In this study, the researchers succeeded in synthesizing a Cre-loxP integrated vector by placing a short DNA ...
Having the gene variant "APOE e4" is said to increase one's risk of developing the ageing-related Alzheimer's disease. However, the gene has a distinct, direct role to play in causing delirium ...
The first steps following gene discovery have become somewhat routine: completing sequencing of the gene, matching the sequence to a known protein pattern (if possible), deciphering gene expression ...
A synthetic PAS (red) is inserted in the 5′ UTR of a transgene. Without ligand, the cleavage destroys the coding region of the mRNA, therefore, losing transgene expression. Ligand binding to the ...
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