Timothy J. Wilson, Nan-Sheng Li, Jun Lu, John K. Frederiksen, Joseph A. Piccirilli, David M. J. Lilley, Olke C. Uhlenbeck Proceedings of the National Academy of ...
Figure 1: Nucleotidyl transfer and RNA hydrolysis reactions catalyzed by multisubunit RNAPs. To address these questions, we used specific biochemical assays of RNAP active-site functions to test ...
Bifunctional acid−base catalysts are highly desirable for industrially relevant chemical processes. Owing to their ability to activate electrophiles and nucleophiles simultaneously, they allow the ...
Most homogenous gold catalyses demand ≥0.5 mol% catalyst loading. Owing to the high cost of gold, these reactions are unlikely to be applicable in medium- or large-scale applications. Here we disclose ...
Enzymology is the study of enzymes and enzyme-catalyzed reactions. Enzymes are biological catalysts that accelerate the rate of biological reactions. They can also perform multiple reactions ...