Life Biosciences is pushing cellular rejuvenation into the clinic with ER-100, an experimental gene ...

A research team has successfully demonstrated the world's first gene-editing treatment for Leber's hereditary optic ...

A new study confirms this long-held theory, discovering that 60 percent of defective genetic pairs impacting the production ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells. However, to be effective, the new gene must make it into a cell's nucleus. The ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

Gene-set analysis seeks to identify the biological mechanisms underlying groups of genes with shared functions. Large language models (LLMs) have shown promise in generating functional descriptions ...

Researchers found that paired pathogenic variants can restore protein function rather than make it worse. This phenomenon ...

Randomized trials of platelet function and genetic testing to guide antiplatelet decisions following PCI have produced notoriously mixed results: now, an updated consensus document aims to fill some ...

For decades, biologists have known that the instructions for life are written in DNA, yet the vast majority of those letters seemed to sit in the dark, doing little that was obvious. Now a new ...

A duplicated gene evolved into a switch that determines sex in frogs, revealing how evolution can safely reshape critical ...

Sometimes, in genetics, two wrongs do make a right. A research team recently showed that two harmful genetic variants, when occurring together in a gene, can restore function—proving a decades-old ...