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Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

In the course of early embryonic development, pluripotent stem cells first give rise to three lineages or ‘germ layers’, which then generate all cell types, tissues and organs of the human body, e.g.

Embryonic germ layers are the fundamental organizing principle in animal development. They provide the structural basis from which tissues and organs arise. During early embryogenesis, cells divide to ...

Advances in genetic and computational tools have enabled researchers to study complex networks of gene expression in individual cells, and the patterns of gene expression in a population of cells ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to develop, ...

Researchers uncovered key networks that simultaneously control pluripotency and readiness for cell death (apoptosis), helping to ensure optimal conditions for embryonic development. The study's ...

Pulmonary arterial hypertension (PAH) is a rare condition that's difficult to treat. The hallmarks of the disease—narrowing of the arterioles and capillaries that deliver blood to the lungs—force the ...

Primordial germ cells, which emerge around day 16 in early human embryos, develop to form oogonia so that eventually, the number of oocytes that are present in an adult female is fixed at birth. After ...