The characteristics of tableted solid dosage drugs often depend on the granulation process, so selecting the most appropriate granulation technique and monitoring the process are crucial Granulation ...

Use of in-process particle size analysis has enabled pharmaceutical scientists and process engineers to track the progress of a granulation process and detect its endpoint. Alon Vaisman. Applications ...

Granulation is a critical unit operation in pharmaceutical manufacturing, where fine powders are agglomerated into granules to improve flow properties, uniformity, and compaction performance. The ...

Formulating drugs to ensure therapeutic consistency, enable rapid development, and allow for cost-effective scale-up has become increasingly challenging. This is especially true in the context of ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...

Fluidized bed spray granulation is a versatile process that integrates the controlled spraying of a binder liquid onto fluidized particles, leading to the formation of agglomerates or granules with ...

Pharmaceutical manufacturing practices are advancing towards a future in which continuous manufacturing processes will be the norm. Developing and applying such techniques is therefore an essential ...

Granulation processes are used for converting light fine powders into large, dense granules to make fast-dissolving drinks, optimized blends for compression tableting, and granules for waste water ...

At the manufacturing level, pharmaceutical manufacturers are leveraging advanced technologies and automation to address challenges such as sample under fill and overfill, detect contaminants and other ...