Sacroiliitis (SI) is reported to develop in up to 20% of patients with inflammatory bowel disease (IBD). While sex and the HLA-B27 allele have been reported to be associated with sacroiliitis in the ...

Researchers in the Center for Immunotherapy at Roswell Park Cancer Institute (RPCI) have evaluated the human leukocyte antigen (HLA), a group of genes that help regulate the body's immune system, for ...

Outcomes of Patients With Double-Hit Lymphoma Who Achieve First Complete Remission Disease relapse remains a major challenge to successful outcomes in patients who undergo allogeneic hematopoietic ...

The Nature Index 2024 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, ...

Philadelphia, February 24, 2023—Researchers at Children’s Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign ...

The human leukocyte antigen (HLA) molecules are proteins expressed on the cell membrane that can activate circulating immune cells, T cells specifically, for targeted cell killing. Alternatively, ...

Researchers at Children’s Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule known as TAPBPR that optimizes the binding and presentation of foreign antigens across the ...