The IGFL2 gene encodes a cytokine found in primates, which are closely related to humans. In the joint tissue of people with rheumatoid arthritis, peripheral helper T (Tph) cells express IGFL2, which ...

For the first time, researchers at the University of British Columbia have demonstrated how to reliably produce an important type of human immune cell-known as helper T cells-from stem cells in a ...

CD4 T helper cells help the body fight infections by signaling other cells to attack germs. Without enough CD4 T cells, the body can't fight diseases like HIV and becomes immunocompromised. HIV ...

The research groups led by Wolfgang Kastenmüller and Georg Gasteiger employed innovative microscopy techniques to observe how specific immune cells, known as T-cells, are activated and proliferate ...

Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with longer PFS, suggesting T-cell composition may serve as a biomarker to ...