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Unfolding the role of Hsp70 chaperones in neurodegeneration
Neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis (ALS) affect millions of people worldwide, yet treatments remain largely limited to symptom ...
Heat-shock protein-70 (HSP70) proteins are molecular chaperones that participate in many cellular processes, such as protein folding, transport across membranes, prevention of protein aggregation and ...
Stress or heat shock proteins (HSPs) such as HSP70 are expressed in response to a wide variety of physiological and environmental insults including heat, reactive oxygen species or anticancer drugs.
StressMarq has announced the release of a new antibody which is specific for cell membrane embedded heat shock protein 70 (HSP70). Clone 1H11 (Catalog No. SMC-249), their anti-HSP70 antibody, is ...
Alzheimer’s disease (AD) is the most prevalent of a large group of related proteinopathies forwhich there is currently no cure. Here, we used Drosophila to explore a strategy to block Aβ42 ...
Proteins are macromolecules synthesized under the control of DNA and perform almost all functions in our cells. However, they must fold into their unique three-dimensional structures to fulfill their ...
Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control ...
ABSTRACT:The functional relationship between thermotolerance and heat shock protein (HSP) expression is well described. However, the intraspecific variation in HSP70 expression and heat resistance is ...
Association of a novel polymorphism G-133C of thymidylate synthase (TYMS) gene with 5-FU-related severe diarrhea in Japanese patients with colorectal cancer ...
Strengthening our leadership position in heat shock and stress related products, Enzo Life Sciences now offers Amp'd™ HSP70 High Sensitivity ELISA Kit – the most sensitive ELISA for Hsp70 detection.
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