“She never wanted anyone to have to naively be in pain without answers," Dern tells PEOPLE of her mother, who died in ...

Multiple Independent Molecular Signals Converge to Validate GRI-0621 as a Potential Disease-Modifying TherapyLA JOLLA, CA, (GLOBE ...

Laura Dern is not just an accomplished actress; she is also a devoted daughter who has taken on a significant mission in honor of her late mother, Diane Ladd. After Ladd’s passing in November 2025 ...

According to GRI Bio, the data shows that GRI-0621 directly impacts the core biology of IPF, with differentially expressed ...

Angiotensin-converting enzyme (ACE) inhibitors were found to be independently associated with reducing all-cause mortality in ...

The phase 2a trial showed GR-0621 met primary and secondary endpoints, demonstrating safety and efficacy over 12 weeks. Phase 2a data show oral GRI-0621 was safe and improved immune and fibrosis ...

Despite the development of cutting-edge genetic testing techniques and considerable progress in our understanding of the genetic basis of idiopathic pulmonary fibrosis (IPF), missing heritability and ...

ACE inhibitor use was associated with reduced all cause mortality in idiopathic pulmonary fibrosis in a matched real world ...

-- BI 765423 has been developed to target IL-11, a key driver of fibrosis -- New study will investigate potential of BI 765423 to improve lung function for patients with idiopathic pulmonary fibrosis ...

What’s more, he explained, several groups have examined existing databases (e.g. Optum, prior clinical trials in IPF, registries) and suggested that metformin therapy in people wiht diabetes with IPF ...

Quantitative CT metrics can be used to define progressive pulmonary fibrosis and have prognostic value in patients with ...