Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or ...

A team led by researchers at the University of Cologne has identified a protein called ANKIB1 that acts as a volume dial for the body’s frontline immune defenses, controlling how strongly cells ...

Virus-associated cancers are a significant and persistent global health challenge, providing unique insight into the relationship between chronic infection ...

The innate immune system serves as the body's first line of defence, rapidly detecting and responding to external pathogens and internal damage. Recent advances in the field have highlighted the ...

Humans are protected by two branches of the immune system. Innate immunity provides built-in defense against widespread characteristics of bacteria and viruses, while adaptive immunity memorizes ...

This is part of a series of stories on the protective role of innate lymphoid cells (ILCs) in the gut and other tissues, focusing on SARS-CoV-2 infection. One area that hasn’t received all that much ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

This story is one in a series marking International Women and Girls in Science Day. Join us as we celebrate some laboratory leaders taking research to new heights. As an assistant professor of ...

This is part of a series on Covid-19 and inflammation related to severe disease and Long Covid. When an individual is first exposed to Covid-19, STING (stimulator of interferon genes) proteins play an ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...