Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital published today in ...

Investigators from Mass General Brigham have developed a way to promote antitumor immunity by hijacking cellular machinery within cancer cells. The study demonstrated that inducing cancer cells to ...

The immune system can work in two ways: the innate immune system reacts to any foreign invaders that are identified by immune cells that look for such pathogens; but the acquired or adaptive immune ...

Our bodies response to invading pathogens through different mechanisms of the immune system. Innate immunity first detects disease and relays a defense signal to activate the second wave of immune ...

Tom Anchordoquy receives funding for this work from the Nationals Institutes of Health through grant # RO1 CA289447. When the first cells appeared on Earth approximately 3.8 billion years ago, viruses ...