While in vivo animal models are commonly employed for pharmacokinetic studies, they are often expensive, low in throughpu,t and typically fail to accurately replicate key characteristics of the human ...
The gastrointestinal (GI) epithelium is the body’s first line of defense to luminal contents such as food, microbiota, pharmaceuticals, and toxins. A small pool of proliferative stem and progenitor ...
In vivo, the intestinal epithelium interacts with the neighboring environment through complex crosstalk, which involves components such as the immune system, tissue microenvironment, and gut microbes.
Microgravity culture during spaceflight enhances microbial infection process in 3D intestinal models
Infectious microbes have evolved sophisticated means to invade host cells, outwit the body's defenses and cause disease. While researchers have tried to puzzle out the complicated interactions between ...
Scientists have studied one ofd the most common laxatives in the world to reveal more about how the regulation of fluid flow ...
The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at ...
Researchers have discovered a way to help aging intestines heal themselves using CAR T-cell therapy. By targeting senescent ...
Stem cells are a hot topic for creating medical treatments. However, scientists still do not fully understand how they choose to divide or differentiate to renew organs. Researchers have now found a ...
Morning Overview on MSN
As our gut ages, key genes go quiet and scientists now know why
As people live longer, the gut quietly accumulates damage that can tip the balance between healthy tissue renewal and chronic ...
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