While in vivo animal models are commonly employed for pharmacokinetic studies, they are often expensive, low in throughpu,t and typically fail to accurately replicate key characteristics of the human ...

Intestinal tuft cells divide to make new cells when immunological cues trigger them. Additionally, in contrast to progenitor- and stem cells, tuft cells can survive severe injury such as irradiation ...

In vivo, the intestinal epithelium interacts with the neighboring environment through complex crosstalk, which involves components such as the immune system, tissue microenvironment, and gut microbes.

Ever notice that as you get older, some foods no longer sit with you the same? This could be due to a breakdown of the intestinal epithelium, a single layer of cells that forms the organ's lining. The ...

FPR2 activation regulates ISC proliferation and differentiation by activating the Wnt, Notch, and Hippo pathways via the PKC-ERK signaling axis. The intestinal epithelium undergoes rapid renewal every ...

Ever notice that as you get older, some foods no longer sit with you the same? This could be due to a breakdown of the intestinal epithelium, a single layer of cells that forms the organ’s lining. The ...