Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor, new research finds. The interrupted non-coding regions in pre-mRNAs, termed ...

The sequences of nonsense DNA that interrupt genes could be far more important to the evolution of genomes than previously thought, according to researchers. Their study of the model organism Daphnia ...

Researchers have long puzzled over why many eukaryotic protein-coding genes are interspersed with segments of noncoding DNA that have no obvious biological function. These so-called introns are ...

Noncoding gene sequences control gene expression and influence disease processes. In the August 1 issue of CELL, researchers from the Gene and Stem Cell Therapy Program at Sydney’s Centenary Institute ...

One of the most long-standing, fundamental mysteries of biology surrounds the poorly understood origins of introns. Introns are segments of noncoding DNA that must be removed from the genetic code ...

Alternative splicing (AS) is a major contributor to transcriptome and proteome diversity. Evolutionary studies help to address questions that are fundamental to understanding this important process.

COLUMBUS, Ohio – Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help ...

The interrupted non-coding regions in pre-mRNAs, termed “introns,” are excised by “splicing” to generate mature coding mRNAs that are translated into proteins. As human pre-mRNA introns vary in length ...