Lupus Science & Medicine

Lectin pathway of complement in SLE: MAP-1 as a marker of haematological manifestations and elevated type I interferon activity

Objective SLE is a systemic autoimmune disease in which the complement system plays a key pathogenic role, yet the ...
The American Journal of Managed Care

iAMD Progression Linked to Dysregulation of Complement Pathways

Dysregulated complement pathways are linked to progression from iAMD to advanced AMD, including NVAMD and GA. Higher systemic levels of C4, C4b, and a reduction in C3 are associated with increased ...
Healio

GT005 gene therapy shows ability to modulate complement pathway in geographic atrophy

Please provide your email address to receive an email when new articles are posted on . In a first-in-human phase 1/2 study, GT005, an AAV2-based one-time investigational gene therapy, showed ...