In the world of biomedical research, the humble lab mouse is a superstar—it’s easy enough to rear in large quantities, shares a considerable amount of core biological processes with humans, and is ...

New research suggests that the commonly used ‘lab mouse’ may display behaviors entirely distinct from their wild-derived counterparts, prompting new considerations for the future of animal-based ...

When laboratory mice step out of their plastic cages and into real soil, their behavior changes so dramatically that it forces a rethink of what stress, health and even “normal” really mean. The story ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

A fundamental challenge in preclinical research is accurately predicting human responses using conventional animal models. Traditional approaches often fail to adequately model human disease, creating ...

Researchers have identified the first mouse strain that is susceptible to severe COVID-19 without the need for genetic modification. This development marks a pivotal step forward in infectious disease ...

Genetically altered mice are valuable tools in biomedical research. The Mutant Mouse Resource and Research Center, located at UC Davis and supported by a grant from NIH, has been providing a national ...