It's no coincidence that our bodies feel a little creakier as we age. The trillions of cells that make up our skeleton age too, and some change in ways that weaken the very structure of our bones.

Cortical bone forms the dense outer shell of long bones and is essential for load bearing, protection of the inner marrow and facilitation of locomotion. Its hierarchical architecture comprises ...

Engineers designing lighter aircraft frames, stronger medical implants, and more efficient vehicle structures keep returning ...

A recent study has uncovered the essential roles of two proteoglycans, biglycan and decorin, in maintaining bone mass, water retention, and bulk/in situ mechanical competence. Through the use of ...

Bone tissue is a complex structure, consisting of mineralized collagen fibers and a variety of non-collagenous proteins, including proteoglycans such as biglycan and decorin. These proteoglycans ...

Normal, regulated growth of skeletal bones is a crucial part of the growth of mammals. This is a complex process involving the growth of cartilaginous cells or chondrocytes, their transformation into ...