Microarray analysis can be performed to assess differences in gene expression between two different samples. After isolating nucleic acids from the two samples, one sample is labeled with a dye that ...

Chromosomal microarray analysis enables the detection of microdeletions/duplications and has become the standard in clinical diagnostic testing for individuals with ...

Expert Rev Mol Diagn. 2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that the ...

Genetic abnormalities have been associated with 6 to 13% of stillbirths, but the true prevalence may be higher. Unlike karyotype analysis, microarray analysis does not require live cells, and it ...

A survey of scientists developing bioprocesses found efficiency to be the top concern, with pressure growing each year to “produce more, do it more quickly, and do so with fewer resources.” 1 Yet, ...

A microarray is a two-dimensional arrangement of biological samples allowing for high-throughput analysis of genetic information. DNA microarrays are commonly used to genotype multiple regions of a ...

Yes, many are attracted to next-generation sequencing, but loyalty to chip-based phenotyping has its rewards, particularly in screens of large sample sets. The microarray, the legacy technology for ...

The research community's rapid acceptance of microarrays notwithstanding, technical challenges remain. Biochip developers continue to grapple with these issues while upgrading their offerings and ...

Serial analysis of gene expression (SAGE) uses mRNA from a sample to create complementary DNA (cDNA) fragments for amplification and sequencing using high-throughput sequencing technology. Credit: ...