In a two-color experiment (panel a in the figure) DNA from individuals of the same species or different tissue from a single individual (e.g., normal and diseased cells) is extracted and ...

A major, multicenter study of microarray performance is a first step in translating the technology from bench to bedside. No technology embodies the rise of 'omic' science more than the DNA microarray ...

Nature uses a common framework when building organisms as different as yeast, worms, fruit flies, mice, and humans. This makes it possible for scientists to learn about how our own genes work by ...

While microarray technology is broadening its applications in genomics and proteomics, the technique remains a vibrant contributor in the area of gene expression. Much of the overall developmental ...

When it comes to enzymes, protein abundance does not necessarily translate into protein activity: Post-translational modifications such as phosphorylation can dramatically alter enzyme function.