Researchers mapped late steps in the formation of the human respirasome, a large protein assembly that drives mitochondrial ...

Scientists uncovered how the amino acid leucine enhances mitochondrial efficiency by preserving crucial proteins that drive energy production. By downregulating the protein SEL1L, leucine prevents ...

He found that heat rapidly impaired electron transport chain complex 1 (ETC1), a mitochondrial protein complex that generates energy. ETC1 impairment set off signaling mechanisms that led to DNA ...

A research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...

Longevity science has spent decades chasing single molecules that might slow aging, but most candidates have delivered modest, inconsistent results. A new line of research is now pointing to a ...

Newly reported research in human tissue and in mice has uncovered a mechanism by which brown fat (brown adipose tissue; BAT) is converted into heat, and identified a control protein that may represent ...

Jeffrey Rathmell, PhD, left, and Darren Heintzman have defined the molecular events of the T cell response to fever temperatures. Fever temperatures rev up immune cell metabolism, proliferation and ...

A technology with the potential to treat ischemic retinopathy in premature infants and diabetic patients has been developed by Professor Byoung Heon Kang and his research team in the Department of ...

A new study shows how one of the cell's most important energy-producing machines is built. Researchers at Karolinska ...