Overall picks to win: 8-8 in Week 17 (173-82-1 for the season) Picks to win with 1-5 confidence: 4-7 (103-64-1) Picks to win with 6-10 confidence: 4-1 (70-18) Overall to cover the spread: 9-6-1 (130-117-9) Cover-the-spread picks with 1-5 confidence: 8-4-1 (107-93-8) Cover-the-spread picks with 6-10 confidence: 1-2 (23-23-1)

Chris Vasile breaks down his favorite NFL picks against the spread for Week 18, including the Carolina Panthers and Baltimore Ravens.

However Sunday night, the 272nd and final game of the regular season, will have winner-take-all stakes as the archrival Pittsburgh Steelers and Baltimore Ravens vie for the AFC North title in the latest installment of their border way. The loser goes gets nothing.

We have a full NFL Week 15 schedule. It started with the Atlanta Falcons knocking off the favored Tampa Bay Buccaneers on Thursday. On Sunday, there will be 14 games, as nobody has a bye week now. Then there will be the Monday night game. Five of those games kick off at 4:25 p.m. ET.

Our NFL Week 18 early picks against the spread start with Saturday's NFC South clash between the Panthers and Buccaneers.

The final weekend of the NFL regular season is upon us, and there are quite a few games that will determine postseason bids and seeding.