Junctional neural tube defect caused by Prickle1 disruption as seen using advanced imaging.(Photo credit: Dr Jian Xiong Wang ...

Neural tube defects, such as Spina bifida, are one of the leading congenital disorders (affecting about one in 1,000 live births worldwide) and are associated with the junctional neurulation. Though ...

How does the neural tube close? A new study uses physics-based modeling to reveal the actin "purse-string" mechanism and cellular coordination that prevents spina bifida.

In about one out of every 1,000 pregnancies, the neural tube, a key nervous system structure, fails to close properly.

The quail is a small, unassuming bird that glides rather than flies and prefers to hide under bushes than to perch on top of ...

A scientific breakthrough that could lead to the eradication of deadly neural tube defects in unborn babies has been ...

In the human embryo, the neural tube forms between the 22nd and 26th day of pregnancy. Later, the brain and spinal cord will develop from this tube. The neural tube forms when an elongated flat tissue ...

When do peripheral nerves develop? Researchers used "mosaic barcodes" to prove that neural crest cells commit to their ...

The first step in shaping the brain is that the neural plate, a sheet-like cell layer, curves to form the neural tube. Assistant Professor Makoto Suzuki of the National Institute for Basic Biology, ...

RosetteArrays, developed at UW–Madison, grow fields of neural rosettes — embroynic versions of down-scaled, simplified brain structures — from stem cells, giving scientists the opportunity to study ...