The new workflow was adapted from an enzymatic DNA tagging technology, DNA-TAG, previously developed in the Devaraj lab. In ...

Gene therapy holds the promise of preventing and curing disease by manipulating gene expression within a patient's cells.

Researchers have created an array of nanopillars that can breach the nucleus of a cell -- the compartment that houses our DNA -- without damaging the cell's outer membrane. This new 'gateway into the ...

From middle school biology we were always taught that the nucleus is the “control center” of the cell, similar to how the brain is the control center of our own bodies. At first glance this makes a ...

Cancer cells are subjected to high mechanical pressure that leads to a rupture of the nuclear envelope when migrating through narrow tissue structures, as in the case of metastasis. DNA would normally ...

This connection between cell metabolism and gene activity helps explain how heart cells grow, age, and sometimes get sick. The research was led by Professor Gergana Dobreva at the Mannheim Medical ...

Researchers at DZHK found that lamin A/C regulates cysteine metabolism, which in turn controls epigenetic gene switches in ...