Cholesterol synthesis and gallstone formation are promoted by trimethylamine-N-oxide (TMAO), a derivative of trimethylamine, which is a metabolite of gut microbiota. However, the underlying mechanisms ...

Gut microbiota produce trimethylamine, which enters the liver via the portal circulation and is primarily oxidized by FMO3 to produce TMAO. TMAO upregulates hepatic PCSK9 gene expression while ...

The gallbladder is a small, grape sized, organ attached to the digestive tract. It secretes a fluid called bile into it in response to a meal. Bile emulsifies dietary fats by increasing their exposure ...

Medically reviewed by Jay N. Yepuri, MD Key Takeaways IBS and gallstones both cause abdominal pain, but the pain location might differ.Gallstones lead to severe pain if they block the bile ducts.IBS ...

Characteristics of survivors with peritoneal mesothelioma. This is an ASCO Meeting Abstract from the 2023 ASCO Annual Meeting I. This abstract does not include a full text component.

Right-side abdominal pain after eating can signal gallstones, liver infection, ulcers or indigestion. Doctor explain causes, ...

Bariatric surgery is widely acknowledged as an effective intervention for morbid obesity, offering significant and sustained weight loss. However, rapid weight reduction following these procedures is ...

Gallbladder problems can become more common during pregnancy due to hormonal changes that slow down digestion and bile flow.