In prion inheritance and transmission, strains are phenotypic variants encoded by protein 'conformations'. However, it is unclear how a protein conformation can be stable enough to endure transmission ...

This is a preview. Log in through your library . Abstract Effectiveness of random amplified polymorphic DNA (RAPD), a technique using 1 10-base primer to amplify random segments of genomic DNA, and ...

In September 6 Nature, Sofia Berlin and Hans Ellegren from Uppsala University, Sweden, examine the controversial clonal inheritance theory for vertebrate mitochondrial DNA (mtDNA) by following ...

The long-QT syndrome and catecholaminergic polymorphic ventricular tachycardia are the most common inherited cardiac channelopathies. 1 Although the disease mechanisms for these two disorders differ, ...

Purpose: The study purpose was to identify the genetic basis of posterior polymorphous corneal dystrophy, an autosomal dominant disorder of the corneal endothelium that is associated with the ...