The majority of patients with cancer receive treatments that are minimally informed by omics data. We propose a precision medicine computational framework, PANOPLY (Precision Cancer Genomic Report: ...
Genome-wide association studies (GWAS) have catalogued hundreds of thousands of genetic variants linked to complex human traits and diseases, with more than 625,000 variant-trait associations across ...
Structural variants (SVs) are the largest source of variations in the human genome and are frequently associated with disease phenotypes. Thus, the identification and characterization of SVs are ...
Predictive modeling compound prioritization has become a central strategy in modern drug discovery, enabling researchers to triage large chemical libraries with increased precision. As compound ...
The majority of patients with cancer receive treatments that are minimally informed by omics data. We propose a precision medicine computational framework, PANOPLY (Precision Cancer Genomic Report: ...