Networks of protein fibers play important roles in living cells. To understand the dynamical behavior of these networks, ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

"For histones, the time window for modifications is incredibly tight because their protein chains are very short," explains first author Denis Yudin, a doctoral student in Nenad Ban's lab. "NAC ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

For decades, Alzheimer’s researchers have watched the same frustrating pattern: the brain’s immune cells detect a threat, ...

Imagine riding a bike. Now imagine riding a bike with an enormous beach ball stuck on your handlebars. That "modification" might change your experience quite a bit. In our cells, molecules called ...

Deubiquitinases (DUBs) are enzymes used by cells to trim protein modifications made from the protein ubiquitin, and thereby regulate proteins. Malfunctioning of DUBs could lead to diseases, including ...

An AI model that reveals how protein modifications link genetic mutations to disease has been developed. Researchers at Baylor College of Medicine (TX, USA) have developed an AI model that reveals how ...

Inside every human cell, proteins are constantly being tagged with small chemical modifications after they’re produced. Known as post-translational modifications, or PTMs, these can change how a ...

Emulsions—mixtures of immiscible liquids such as oil and water—rely on surface‐active agents to stabilise dispersed droplets against coalescence and creaming. Proteins are among the most versatile ...