Findings suggest that new genes can form by repurposing fragments of ancestral genes while incorporating entirely new coding regions (the protein-coding parts of the DNA). This innovative concept ...

A research team has unveiled a breakthrough in understanding how specific genetic sequences, known as pseudogenes, evolve. Rice University's Peter Wolynes and his research team have unveiled a ...

Rice University’s Peter Wolynes and his research team have unveiled a breakthrough in understanding how pseudogenes evolve. Led by Wolynes, the D.R. Bullard-Welch Foundation Professor of Science, ...

Using bright X-rays from the Department of Energy's SLAC National Accelerator Laboratory and Lawrence Berkeley National ...

The number of known proteins is infinitely small in comparison to the universe of possible proteins, which could in theory be realized. Yet these known proteins are the only major training ground for ...

Protein design is crucial for the treatment of human diseases, but traditional protein design methods have some limitations. Site-directed mutagenesis is highly dependent on the physiological ...

A new platform combines rational protein design with continuous evolution to discover functional molecules more efficiently. In medicine and biotechnology, the ability to evolve proteins with new or ...

The genetic code has given rise to the enormous diversity of proteins we see in nature—and rearranging the order of codons that make up a protein’s sequence leads to an immense variety of structure ...

Protein sequencing presents different challenges than nucleic acid sequencing, meaning that proteomics has yet to benefit as much as genomics from the next-generation sequencing revolution. However, ...

Making high-performance proteins for medicines or consumer products can take trial after trial of tweaks, experiments and fine-tuning. A new machine learning framework squeezes all that into a single ...